751 research outputs found

    Evaluation of Wayfinding Design of Senior Residential Communities

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    Wayfinding is defined as the ability of an individual to find their way in an environment. Long term care (LTC) communities are very difficult for wayfinding, especially for persons with cognitive impairment. There is very little scientific evidence for design elements to assist individuals with wayfinding. In this study we created a tool based on the literature to evaluate the quality of LTC communities for wayfinding design. For this study, the tool was piloted to review the wayfinding design of seven LTC communities. Descriptive statistics were used to determine the highest and lowest scored areas. A table of mean and mode scores and the range will be included in the poster and discussed. This information can be used to determine what alterations can be made to these communities to increase their wayfinding effectiveness

    Claim your online scholarly presence: ORCiD

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    Presented as a Small Group/Roundtable Discussion at 2020 IUSM Education Day.Claiming, maintaining, and tracking research output is crucial to a researcher’s continued visibility and impact. Tracking scholarly output and cultivating information about a researcher's work is made possible with online scholarly profile tools. As the most widely accepted unique identifier for authors, ORCiD IDs are increasingly required for: paper submissions to journals, grant submissions, and various NIH research training and career development awards. Attendees participated in hands on activities to set up profiles, and discover more information about tracking their impact going forward, and utilize existing connections between different scholarly profile tools. Learning objectives: • List reasons why maintaining scholarly profiles is important to researchers • Describe the benefits of several scholarly profile tools • Set up and/or update your scholarly profile(s

    Bibliometric analysis of publications on healthcare disparities among sexual and gender minorities: an exploratory study

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    Academic and scientific literature related to healthcare disparities among sexual and gender minorities has increased significantly over the past decade. For this study, a bibliometric analysis will be applied to examine the characteristics, as well as the growth and authorship patterns of worldwide research output, addressing issues related to barriers and disparities of the availability or access to medical services for the LGBTQ population. For this exploratory study, we used the Web of Science database, one of the most widely multidisciplinary databases, that provides the analytical tools for bibliometric calculations. For this analysis, we conducted a bibliographic search on the topic of healthcare disparities in order to collect the representative documents about the topic and to identify authors, document types, year of publications, sources, main thematic areas, most productive institutions, languages and most productive countries of research output. We used an open-source Bibliometrix/Biblioshiny R-package to conduct quantitative analysis. This approach aims to inform the development and trends of research outputs to understand what this research is focusing on, identify research productivity and topic trends

    Concert recording 2015-04-29b

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    [Track 01]. Chaconne / Tomaso Antonio Vitali -- [Track 02]. Thème original varié, op. 15 / Henryk Wieniawski -- [Track 03]. Violin sonata no. 3, op. 108. Allegro ; Adagio ; Un poco e con sentiment ; Presto agitato / Johannes Brahms -- [Track 04]. Cantabile for violin and piano / Niccoló Paganini

    Who is talking about my research: introduction to altmetrics

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    Presented as a poster at 2021 IUSM Education Day. View the presentation recording here: [LINK]https://purl.dlib.indiana.edu/iudl/media/s85940fh8j[/LINK]The poster will provide a roadmap of how to track and use alternative metrics (altmetrics) to provide evidence of attention or engagement of individual research outlets. Altmetrics are non-traditional metrics proposed as an alternative/complement to citation impact metrics. They provide information about the attention and influence of research of an article or publication and are based on interactions and conversations about scholarly content that occur online, mainly on social media platforms. One of the benefits of altmetrics is that they can accrue sooner than traditional metrics (citations) as they do not depend on the long process of conventional scholarly communication. Examples of altmetrics include mentions on Twitter, in news releases, in blogs, citations in policy documents, number of downloads, and more. As altmetrics are becoming more popular than ever in the evaluation of research, you can include them in your CV, grant proposal, personal website, and your promotion and tenure dossier. This poster shows useful sources and tools to track alternative metrics

    Preparing FMHC Students For Life After Graduation

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    The pages you have before you are a complete chronicle of our journey through the design thinking process. We were asked a pressing question: “how can Honors students better prepare for life after graduation?” This question launched a four-month journey, for which we were given the map of the design thinking process. This map was unique in that it told us what terrain we would be navigating, but not how to get to the next destination. Not directly, anyway. Every section of terrain had many paths, and plenty of open space to forge our own. From the rolling moors of defining, the treacherous ocean of empathizing, and the jagged cliffs of redefining—to the plentiful woodlands of ideating, the uncharted wilderness of prototyping, and finally, the open plains of testing, we wound our way through the problem, and came out on the other side with a solution. Afterwards, we compiled all our newly-forged maps into a portfolio of our innovation. We are proud to share our progress—how we went from standing before a real-world question to creating the concept of a Laker Legend web application. Thank you for taking the time to explore our journey—perhaps our insights can help you in some exploration of your own

    Évaluation de l’efficacité du programme Global Medical Student Partnership dans les études de médecine de premier cycle

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    Background: The Global Medical Student Partnership (GMSP) is, a medical student-led international initiative to promote accessible Global Health learning. This study aims to evaluate the effectiveness of the GMSP program in meeting its learning objectives. Methods: Canadian and international medical student pairs met online monthly (January-May 2018) to discuss global health-related medical cases. Students then reviewed cases with local GMSP peers and faculty experts. A mixed-methods study was performed to evaluate whether the objectives of the program had been achieved. 26 of 32 (81.3%) students completed a questionnaire, and 13 (40.6%) also participated in one-on-one semi-structured interviews. Descriptive statistics and thematic analysis were used to analyze students’ perspectives on skill development through GMSP. Results: GMSP students agreed or strongly agreed that international collaboration and communication skills were more important to them following program participation (92.3%, 92.3% respectively). Many expressed that after GMSP, they knew more about their healthcare system, practices abroad and how to solve complex health issues (92.3%, 84.6%, 61.5% respectively). Qualitative data showed GMSP improved students’ communication and presentation skills, provided a foundation for international relationships, fostered appraisal of diverse health systems, and furthered students’ understanding of health advocacy. Conclusions: Our findings demonstrate that GMSP met its original objectives by providing students with opportunities to engage in international collaborations and to further develop their skills in advocacy, communication, and health-systems research. This program may be an important addition to medical education as it makes use of technology and peer-to-peer exchange to enable global health learning.Contexte : Le Global Medical Student Partnership (GMSP) est une initiative d’envergure internationale menée par des étudiants en médecine qui vise à favoriser la formation en santé mondiale.  La présente étude consiste à évaluer l’efficacité du programme GMSP pour atteindre ses objectifs d’apprentissage. Méthodologie : Des paires d’étudiants en médecine canadiens et étrangers se sont rencontrés en ligne tous les mois, entre janvier et mai 2018, pour discuter de situations cliniques en santé mondiale.  Après la rencontre, ces situations cliniques ont été revues par des pairs locaux du programme GMSP et des experts du corps professoral. On a effectué une étude à devis mixte pour déterminer si les objectifs du programme avaient été atteints. 26 des 32 (81,3 %) étudiants ont répondu à un questionnaire et 13 (40,6 %) ont aussi pris part à des entrevues individuelles semi-dirigées. Des statistiques descriptives et une analyse thématique ont été utilisées analyser les perceptions des étudiants sur le développement d’habiletés par le programme GMSP. Résultats : Les étudiants participant au programme GMSP étaient d’accord ou très en accord pour dire que les habiletés à la collaboration internationale et à la communication étaient plus importantes à leurs yeux après la participation au programme (92.3%, 92,3%, respectivement). Bon nombre ont affirmé qu’après le programme GMSP, ils en connaissaient plus sur leur système de soins de santé, les pratiques à l’étranger et les façons de résoudre des problèmes de santé complexes (92,3 %, 84,6 %, 61,5 % respectivement). Des données qualitatives ont montré que le programme GMSP a amélioré les aptitudes à la communication et des techniques de présentation.  Elles ont servi à établir des relations à l’international, à évaluer divers systèmes de soins de santé et à mieux comprendre la promotion de la santé et à militer en faveur de celle-ci. Conclusions : Nos résultats montrent que le programme GMSP a atteint ses objectifs de départ puisqu’il a donné aux étudiants des occasions de collaboration internationale et leur a permis de développer davantage leurs habiletés en matière de défense des droits, de communication, et de recherche sur les systèmes de soins de santé. Ce programme pourrait s’avérer un important complément à la formation médicale parce qu’il utilise la technologie et des échanges pairs-pairs pour l’apprentissage des enjeux de santé mondiaux

    Calcium Phosphate Nanoparticle-Based Vaccines as a Platform for Improvement of HIV-1 Env Antibody Responses by Intrastructural Help

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    Incorporation of immunodominant T-helper epitopes of licensed vaccines into virus-like particles (VLP) allows to harness T-helper cells induced by the licensed vaccines to provide intrastructural help (ISH) for B-cell responses against the surface proteins of the VLPs. To explore whether ISH could also improve antibody responses to calcium phosphate (CaP) nanoparticle vaccines we loaded the nanoparticle core with a universal T-helper epitope of Tetanus toxoid (p30) and functionalized the surface of CaP nanoparticles with stabilized trimers of the HIV-1 envelope (Env) resulting in Env-CaP-p30 nanoparticles. In contrast to soluble Env trimers, Env containing CaP nanoparticles induced activation of naïve Env-specific B-cells in vitro. Mice previously vaccinated against Tetanus raised stronger humoral immune responses against Env after immunization with Env-CaP-p30 than mice not vaccinated against Tetanus. The enhancing effect of ISH on anti-Env antibody levels was not attended with increased Env-specific IFN-γ CD4 T-cell responses that otherwise may potentially influence the susceptibility to HIV-1 infection. Thus, CaP nanoparticles functionalized with stabilized HIV-1 Env trimers and heterologous T-helper epitopes are able to recruit heterologous T-helper cells induced by a licensed vaccine and improve anti-Env antibody responses by intrastructural help

    Enhanced X-ray Emission from the Most Radio-Powerful Quasar in the Universe's First Billion Years

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    We present deep (265 ks) Chandra X-ray observations of PSO J352.4034-15.3373, a quasar at z=5.831 that, with a radio-to-optical flux ratio of R>1000, is one of the radio-loudest quasars in the early universe and is the only quasar with observed extended radio jets of kpc-scale at z6z \gtrsim 6. Modeling the X-ray spectrum of the quasar with a power law, we find a best fit of Γ=1.990.28+0.29\Gamma = 1.99^{+0.29}_{-0.28}, leading to an X-ray luminosity of L210=1.260.33+0.45×1045 erg s1L_{2-10} = 1.26^{+0.45}_{-0.33} \times 10^{45}\ {\rm erg}\ {\rm s}^{-1} and an X-ray to UV brightness ratio of αOX=1.36±0.11\alpha_{\rm OX} = -1.36 \pm 0.11. We identify a diffuse structure 50 kpc (8{\sim}8^{\prime\prime}) to the NW of the quasar along the jet axis that corresponds to a 3σ3\sigma enhancement in the angular density of emission and can be ruled out as a background fluctuation with a probability of P=0.9985. While with few detected photons the spectral fit of the structure is uncertain, we find that it has a luminosity of L2101044 erg s1L_{2-10}\sim10^{44}\ {\rm erg}\ {\rm s}^{-1}. These observations therefore potentially represent the most distant quasar jet yet seen in X-rays. We find no evidence for excess X-ray emission where the previously-reported radio jets are seen (which have an overall linear extent of 0.280.^{\prime\prime}28), and a bright X-ray point source located along the jet axis to the SE is revealed by optical and NIR imaging to not be associated with the quasar.Comment: 16 pages, 7 Figures. Accepted for publication the Astrophysical Journa

    Anti-nausea effects and pharmacokinetics of ondansetron, maropitant and metoclopramide in a low-dose cisplatin model of nausea and vomiting in the dog: a blinded crossover study

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    Nausea is a subjective sensation which is difficult to measure in non-verbal species. The aims of this study were to determine the efficacy of three classes of antiemetic drugs in a novel low dose cisplatin model of nausea and vomiting and measure change in potential nausea biomarkers arginine vasopressin (AVP) and cortisol. A four period cross-over blinded study was conducted in eight healthy beagle dogs of both genders. Dogs were administered 18 mg/m2 cisplatin intravenously, followed 45 min later by a 15 min infusion of either placebo (saline) or antiemetic treatment with ondansetron (0.5 mg/kg; 5-HT3 antagonist), maropitant (1 mg/kg; NK1 antagonist) or metoclopramide (0.5 mg/kg; D2 antagonist). The number of vomits and nausea associated behaviours, scored on a visual analogue scale, were recorded every 15 min for 8 h following cisplatin administration. Plasma samples were collected to measure AVP, cortisol and antiemetic drug concentrations
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